Strange Tales was a pre-Marvel title used to help usher in the Marvel Universe. Although some of the one-off stories have subsequently become canon (like the ones about Fin Fang Foom and Ulysses Bloodstone), it wasn’t until issue #101 that it was a canonical book.
#101-109: Human Torch solo stories
#110-134: Human Torch/Dr. Strange
#135-169: Dr. Strange/Nick Fury
#170-181: Platform to introduce/feature new characters like Brother Voodoo, Golem, Adam Warlock, etc.