Bottom line: He fights Deadpool, meeting him for the first time.
Longer version:
James “Guardian” Hudson asked Logan to see if Garrison Kane is doing okay. Logan goes to Kane’s apartment but Deadpool is there, also looking for Kane (and Copycat, who he lives with).
So they fight.
Then they race to be the first to find Vanessa and Kane.
Then Wolverine and Deadpool fight again, but this time alongside Vanessa.
Simple issue. Lots of violence.