Deadpool teams up with It The Living Colossus. And before you say that this is a dumb team-up, go back and read some of his early appearances. They were actually pretty good. But then, I was a sucker for the old Marvel Team Up/Two-In-One books of the late ’70s/early ’80s.
Deadpool is hired to lead a submarine expedition to find a missing person.
Apparently, the way your reach him is via Brian Michael Bendis’ message board.
The missing person is the consciousness who has inhabited It The Living Colossus.
There’s a rescue of sorts but nothing all that consequential. That’s OK, though–it’s a fun story. One of the better recent Deadpool tales.