The Dire Wraiths and the Dire Witches are kidnapping human children, and ROM tries to stop them. Turns out, the Dires are feeding an extradimensional being called the Dweller on the Threshold, so ROM has to get help from Dr. Strange.
We learn that The Living Tribunal is partially behind it all—he’s trying to allow the Dweller on to our planet because Dr. Strange is too powerful, and he brings in The In-Betweener as his muscle.
ROM is pretty dispensable here.