SPECTACULAR SPIDER-MAN #176-177 (1991)

Corona! Truly a villain for the 2020s! I mean, the tag lines on that cover could have been ripped from CNN or the Daily News in 2021!

She’ll appear one more time, in the pages of Spider-Man Unlimited in 1993, where the author of this story, Kurt Busiek, does a little addendum to this same story.

Spidey himself gets sick and turns to his science buddies Reed Richards and Harry Osborn (himself a lab-created villain and victim of circumstace) for help.

Corona is the creation of a lab, an accidental villain who can pity but also know must be stopped–just like Lizard, Morbius, and several other Spidey foes.

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